There are currently no results that match your search, please try again.
There are currently no results that match your search, please try again.
This episode features Technical Director, Adrian La Porta, exploring the miniaturization of Active Pharmaceutical Ingredients (APIs) manufacturing. Adrian takes us through the journey of how small molecule APIs, the backbone of many essential medicines, are being revolutionized by embracing cutting-edge technologies and sustainable practices.
Through this 'In Short' episode, Adrian delves into the challenges and breakthroughs in pharmaceutical manufacturing, exploring how new approaches like process intensification, automation, and continuous processing can lead to more agile, cost-effective, and environmentally friendly production methods.
Click the 'play button' above to listen in, or read our 5 Key Takeaways from this episode below...
The episode highlights the transformative research and development in small molecule Active Pharmaceutical Ingredients, emphasizing the generation of new, more complex, and targeted molecules. This revolution is pivotal for advancing the mainstay of essential medicines globally.
Adrian La Porta discusses the limitations of current manufacturing practices, particularly batch chemistry, in meeting the modern demands for higher volumes, complex products, and faster production at lower costs, all while minimizing environmental impact. He points out the inefficiencies and hazards of scaling up production using traditional methods.
The podcast emphasizes the shift towards process intensification and automation as solutions to the challenges faced by traditional manufacturing. These innovations promise to deliver lean and agile manufacturing, reducing waste, improving quality, and enabling the production of more complex molecules more efficiently.
A significant focus is on the concept of miniaturization and continuous processing as part of a new paradigm in drug manufacturing. This approach not only reduces the environmental footprint and costs but also enhances safety and quality by enabling smaller, more controlled, and flexible production processes.
Finally, Adrian discusses the systemic and regulatory barriers to adopting these new manufacturing technologies but also highlights the compelling need for change driven by the demand for affordable, sustainable medicines. He advocates for embracing these new technologies to overcome current limitations and transform pharmaceutical manufacturing.
The podcast emphasizes the urgent need for innovation in pharmaceutical manufacturing to address current challenges and future demands.
